Pinches of salt at the ready. A Mass Effect 3 packshot apparently obtained from EA's online store seems to suggest that Mass Effect 3 could support Xbox 360 Kienct.
The claim comes from the BioWare forums, though any reference to the game seems to have been removed from the EA Store.
Last week Microsoft appeared to accidentally confirm Kinect compatibility for Ubisoft's Ghost Recon: Future Soldier.
It wouldn't be a surprise to see Microsoft making greater strides into the traditional games market with Kinect at this E3. That's one thing Sony has done particularly well with PlayStation Move, with titles such as Killzone 3, MAG and RUSE supporting the device.