It all kicks off with pre-event drinks at The Kings Head, Chiswell Street from 5pm, courtesy of Sennheiser and Gem Distribution.
The champagne reception sponsored by IGA Worldwide then follows at 6pm, when the night will get fully underway.
There are 17 awards up for grabs, including Star Store, Games Publisher, Marketing Team, Sales Team and Game Campaign.
Click here to see the full set of categories and Finalists.
"Every major company will be in attendance on April 19th and we're delighted to have taken the MCV Awards to another level. We're packing more into the night, including a performance by our own pub landlord Al Murray, and the awards themselves are as coveted as ever," commented MCV publisher and Intent Media managing director Stuart Dinsey.
"It is the industry itself that choose the winners. The awards recognise effort, innovation and commercial success. There is no greater accolade."
Sponsors include gold partner Xbox 360, retail partner Nintendo and silver partner Nvidia, plus Kiss FM, System 3, Mice Domino and GamerTV.