The news comes after five members of the company’s previous Board of directors, including CEO Paul Eibler, left the firm last month following a shareholder revolt.
Take 2 senior VP of finance Lainie Goldstein will take over as interim CFO until a permanent replacement for Winters is found.
“Karl oversaw finance at Take 2 during challenging times for the company," said acting Take 2 CEO Ben Feder.
“We thank Karl for his years of service to Take 2. He was instrumental in assembling a highly competent financial team that will serve us well in the future. We appreciate Karl's hard work and his continued support during the transition.
"I look forward to working closely with Lainie as we continue to address Take 2's challenges aggressively and swiftly so that employees can focus on building the company's bright future."