For the first time in the vent's history, this year's E3 will host a press conference from Bethesda.
The immediate conclusion? Fallout 4.
Although of course the studio has a number of other projects on the go, including the new Doom and the console version of The Elder Scrolls Online, as well as online PC title Battlecry.
The last Fallout game was released was 2010's Fallout: New Vegas, which was based very much on the build debuted with 2008's Fallout 3. The series first arrived back in 1997 and has acted very much as a counterweight to the more fantasy-based Elder Scrolls series.
Other Bethesda games that could potentially be in line for a sequel include Dishonored, Rage, Wolfenstein and The Evil Within.