Guitar Hero III: Legends of Rock will be released this autumn on PC and Mac.
The new versions will feature multiplayer battle modes, boss battles and un-lockable content.
It will include over 70 songs, and an expanded online mode, reported Game Daily.
"Working with such a wildly successful franchise and helping to strengthen an already powerful brand has us feeling like rock stars ourselves, only without the fame, money or musical talent," said Ted Staloch, executive vice president, publishing for Aspyr.
"But even without Slash's chops, we still have what it takes to bring the best music game on the planet to PC and Mac gamers. Aspyr's expertise in developing and publishing for these platforms means that we will deliver a game that wails just as hard as it does on consoles but feels natural on this audience's chosen platform."